Epigenetics at the epicenter of modern medicine.

Role of Epigenetics in Biology and Human Diseases

For a long time, scientists have tried to describe disorders just by genetic or environmental factors. However, the role of epigenetics in human diseases has been considered from a half of century ago. In the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...

Epigenetics in diagnosis of colorectal cancer

Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the...

The Prospects of Epigenetics in Neuroscience

The Role of Epigenetics in Cancer Drug Resistance

Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, histone modification, and microRNAs gene deregulation are the most known epigenetic changes in different stages of cancer. Since every tumor has its own specific epigenome, any abnormal pattern is a potential biomarker for classification of different types of tumors. Despite, tumorigenesis, abnorma...

Role of ethnopharmacology in the development of modern medicine

According to WHO, about three-quarters of the world population rely upon traditional medicine (TM) mainly herbs for the healthcare. Apparently all primitive peoples used herbs-often in a sophisticated way. By the middle of the 19th century at least 80% of all medicines were derived from herbs. Then came the revolution inspired by the development of the pharmaceutical industry and synthetic drug...